GWAS-related meQTLs across different cancer types

We identified 2,214,458 meQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).



e.g., "BLCA"
e.g., "rs10000012"
e.g., "CTBP1"
e.g., "cg02980000"
Cancer type
QTL type
tagSNP
LD
SNP ID
SNP position (hg19)
alleles
probe
Gene position (hg19)
Gene
Beta
t-stat
r
p-value
Traits
BLCA trans rs11098499 0.865 rs4507344 chr4:120307485 C/A cg19731845 chr4:166199412 KLHL2;GK3P 0.35 6.2 0.3 1.5E-9 Corneal astigmatism;
BLCA trans rs561341 0.623 rs4795665 chr17:30233657 C/T cg20587970 chr11:113659929 NA -0.83 -12.56 -0.54 1.67E-30 Hip circumference adjusted for BMI;
BLCA trans rs4889911 1 rs4889910 chr17:77839795 C/T cg02933969 chr8:12612811 LONRF1 0.43 6.1 0.3 2.62E-9 Electroencephalogram traits;
BLCA trans rs4889911 1 rs4889910 chr17:77839795 C/T cg05052031 chr3:33138450 TMPPE;GLB1 0.47 6.55 0.32 1.83E-10 Electroencephalogram traits;
BLCA trans rs4889911 1 rs4889910 chr17:77839795 C/T cg09399498 chr7:86782128 DMTF1 0.46 6.47 0.32 2.94E-10 Electroencephalogram traits;
BLCA trans rs4889911 1 rs4889910 chr17:77839795 C/T cg21691089 chr1:8938721 ENO1 0.43 6.15 0.3 2.02E-9 Electroencephalogram traits;
BLCA trans rs561341 1 rs537166 chr17:30326827 C/T cg27661571 chr11:113659931 NA -0.51 -6.26 -0.31 1.05E-9 Hip circumference adjusted for BMI;
BLCA trans rs78049276 0.688 rs61075980 chr4:148374767 G/A cg13149281 chr14:23389818 RBM23;PRMT5 -0.69 -8.58 -0.4 2.47E-16 Pulse pressure;
BLCA trans rs629535 0.814 rs651985 chr8:70054966 G/A cg21567404 chr3:27674614 NA 0.87 14.46 0.6 4.76E-38 Dupuytren's disease;
BLCA trans rs629535 0.814 rs72654071 chr8:70079484 A/G cg21567404 chr3:27674614 NA -0.87 -14.43 -0.59 6.31E-38 Dupuytren's disease;
BLCA trans rs11109072 0.655 rs78546782 chr12:98031173 C/T cg25564535 chr2:98329463 ZAP70 -0.59 -6.95 -0.34 1.59E-11 Obesity (early onset extreme);
BLCA trans rs3780486 0.846 rs7865745 chr9:33140976 A/G cg04842962 chr6:43655489 MRPS18A -1.07 -28.16 -0.82 4.68E-95 IgG glycosylation;
BLCA trans rs61931739 0.517 rs7975714 chr12:34055611 T/C cg13010199 chr12:38710504 ALG10B 0.53 8.46 0.4 6.04E-16 Morning vs. evening chronotype;
BLCA trans rs208520 0.69 rs851467 chr6:66802721 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -15.81 -0.63 1.31E-43 Exhaled nitric oxide output;
BLCA trans rs2880058 0.521 rs870939 chr1:162004361 A/G cg24156658 chr11:65122092 TIGD3 0.39 6.02 0.3 4.0E-9 QT interval;